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1e4o
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| - | ==== | + | ==Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question== |
| - | <StructureSection load='1e4o' size='340' side='right'caption='[[1e4o]]' scene=''> | + | <StructureSection load='1e4o' size='340' side='right'caption='[[1e4o]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1e4o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E4O FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e4o OCA], [https://pdbe.org/1e4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e4o RCSB], [https://www.ebi.ac.uk/pdbsum/1e4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e4o ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e4o OCA], [https://pdbe.org/1e4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e4o RCSB], [https://www.ebi.ac.uk/pdbsum/1e4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e4o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHSM_ECOLI PHSM_ECOLI] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Cottaz S]] |
| + | [[Category: Driguez H]] | ||
| + | [[Category: Geremia S]] | ||
| + | [[Category: Johnson LN]] | ||
| + | [[Category: McCleverty C]] | ||
| + | [[Category: Watson KA]] | ||
Current revision
Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question
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