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1e4x
From Proteopedia
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| - | [[Image:1e4x.png|left|200px]] | ||
| - | + | ==crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment== | |
| - | + | <StructureSection load='1e4x' size='340' side='right'caption='[[1e4x]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | === | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1e4x]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E4X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e4x OCA], [https://pdbe.org/1e4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e4x RCSB], [https://www.ebi.ac.uk/pdbsum/1e4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e4x ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1e4x]] is a 6 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/IGKC_MOUSE IGKC_MOUSE] | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/1e4x_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e4x ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Hahn | + | [[Category: Synthetic construct]] |
| - | [[Category: Hoehne | + | [[Category: Hahn M]] |
| - | [[Category: Misselwitz | + | [[Category: Hoehne W]] |
| - | [[Category: Schneider-Mergener | + | [[Category: Misselwitz R]] |
| - | [[Category: Welfle | + | [[Category: Schneider-Mergener J]] |
| - | [[Category: Wessner | + | [[Category: Welfle K]] |
| - | [[Category: Winkler | + | [[Category: Wessner H]] |
| - | [[Category: Zahn | + | [[Category: Winkler D]] |
| - | + | [[Category: Zahn G]] | |
| - | + | ||
| - | + | ||
Current revision
crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment
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