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1e5g

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{{Seed}}
 
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[[Image:1e5g.png|left|200px]]
 
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<!--
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==Solution structure of central CP module pair of a pox virus complement inhibitor==
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The line below this paragraph, containing "STRUCTURE_1e5g", creates the "Structure Box" on the page.
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<StructureSection load='1e5g' size='340' side='right'caption='[[1e5g]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1e5g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5G FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5g OCA], [https://pdbe.org/1e5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5g RCSB], [https://www.ebi.ac.uk/pdbsum/1e5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5g ProSAT]</span></td></tr>
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{{STRUCTURE_1e5g| PDB=1e5g | SCENE= }}
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</table>
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== Function ==
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===SOLUTION STRUCTURE OF CENTRAL CP MODULE PAIR OF A POX VIRUS COMPLEMENT INHIBITOR===
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[https://www.uniprot.org/uniprot/VCP_VACCC VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11243823}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11243823 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5g_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11243823}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5g ConSurf].
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1E5G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein., Henderson CE, Bromek K, Mullin NP, Smith BO, Uhrin D, Barlow PN, J Mol Biol. 2001 Mar 16;307(1):323-39. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11243823 11243823]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Vaccinia virus Copenhagen]]
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[[Category: Vaccinia virus]]
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[[Category: Barlow PN]]
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[[Category: Barlow, P N.]]
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[[Category: Bromek K]]
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[[Category: Bromek, K.]]
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[[Category: Henderson CE]]
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[[Category: Henderson, C E.]]
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[[Category: Mullin NP]]
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[[Category: Mullin, N P.]]
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[[Category: Smith BO]]
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[[Category: Smith, B O.]]
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[[Category: Uhrin D]]
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[[Category: Uhrin, D.]]
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[[Category: Complement]]
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[[Category: Module]]
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[[Category: Nmr]]
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[[Category: Protein structure]]
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[[Category: Vaccinia virus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:10:38 2008''
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Current revision

Solution structure of central CP module pair of a pox virus complement inhibitor

PDB ID 1e5g

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