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1ebv

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[[Image:1ebv.png|left|200px]]
 
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{{STRUCTURE_1ebv| PDB=1ebv | SCENE= }}
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==OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID==
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<StructureSection load='1ebv' size='340' side='right'caption='[[1ebv]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ebv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EBV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene>, <scene name='pdbligand=SCL:ACETIC+ACID+SALICYLOYL-AMINO-ESTER'>SCL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ebv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ebv OCA], [https://pdbe.org/1ebv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ebv RCSB], [https://www.ebi.ac.uk/pdbsum/1ebv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ebv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGH1_SHEEP PGH1_SHEEP] May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/1ebv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ebv ConSurf].
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<div style="clear:both"></div>
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===OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID===
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==See Also==
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*[[Cyclooxygenase 3D structures|Cyclooxygenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[1ebv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EBV OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:011723249</ref><references group="xtra"/>
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[[Category: Ovis aries]]
[[Category: Ovis aries]]
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[[Category: Prostaglandin-endoperoxide synthase]]
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[[Category: Fitzgerald DJ]]
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[[Category: Connor, S J.O.]]
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[[Category: Loll PJ]]
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[[Category: Fitzgerald, D J.]]
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[[Category: O'Connor SJ]]
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[[Category: Loll, P J.]]
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[[Category: Sharkey CT]]
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[[Category: Sharkey, C T.]]
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[[Category: Monotopic membrane protein]]
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[[Category: Oxidoreductase]]
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Current revision

OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID

PDB ID 1ebv

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