1eic

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{{Seed}}
 
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[[Image:1eic.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A==
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The line below this paragraph, containing "STRUCTURE_1eic", creates the "Structure Box" on the page.
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<StructureSection load='1eic' size='340' side='right'caption='[[1eic]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1eic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EIC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eic OCA], [https://pdbe.org/1eic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eic RCSB], [https://www.ebi.ac.uk/pdbsum/1eic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eic ProSAT]</span></td></tr>
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{{STRUCTURE_1eic| PDB=1eic | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/1eic_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eic ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11742124}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11742124 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_11742124}}
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==About this Structure==
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1EIC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EIC OCA].
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==Reference==
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Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution., Chatani E, Hayashi R, Moriyama H, Ueki T, Protein Sci. 2002 Jan;11(1):72-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11742124 11742124]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Pancreatic ribonuclease]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Chatani E]]
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[[Category: Chatani, E.]]
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[[Category: Hayashi R]]
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[[Category: Hayashi, R.]]
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[[Category: Moriyama H]]
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[[Category: Moriyama, H.]]
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[[Category: Ueki T]]
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[[Category: Ueki, T.]]
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[[Category: Bovine pancrea]]
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[[Category: Hydrolase]]
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[[Category: Ribonuclease]]
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[[Category: Rnase some]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:44:48 2008''
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Current revision

CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A

PDB ID 1eic

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