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1eot

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{{Seed}}
 
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[[Image:1eot.png|left|200px]]
 
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==SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE==
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The line below this paragraph, containing "STRUCTURE_1eot", creates the "Structure Box" on the page.
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<StructureSection load='1eot' size='340' side='right'caption='[[1eot]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1eot]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EOT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eot OCA], [https://pdbe.org/1eot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eot RCSB], [https://www.ebi.ac.uk/pdbsum/1eot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eot ProSAT]</span></td></tr>
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{{STRUCTURE_1eot| PDB=1eot | SCENE= }}
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</table>
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== Function ==
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===SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE===
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[https://www.uniprot.org/uniprot/CCL11_HUMAN CCL11_HUMAN] In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_9712872}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 9712872 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/1eot_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_9712872}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eot ConSurf].
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1EOT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EOT OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation., Crump MP, Rajarathnam K, Kim KS, Clark-Lewis I, Sykes BD, J Biol Chem. 1998 Aug 28;273(35):22471-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9712872 9712872]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Crump, M P.]]
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[[Category: Crump MP]]
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[[Category: Rajarathnam, K.]]
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[[Category: Rajarathnam K]]
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[[Category: Sykes, B D.]]
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[[Category: Sykes BD]]
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[[Category: Ccr3]]
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[[Category: Chemokine]]
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[[Category: Cytokine]]
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[[Category: Eosinophil]]
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[[Category: Eotaxin]]
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[[Category: Protein synthesis]]
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[[Category: Solution structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:22:40 2008''
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Current revision

SOLUTION NMR STRUCTURE OF EOTAXIN, MINIMIZED AVERAGE STRUCTURE

PDB ID 1eot

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