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1eqp

From Proteopedia

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{{Seed}}
 
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[[Image:1eqp.png|left|200px]]
 
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==EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS==
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The line below this paragraph, containing "STRUCTURE_1eqp", creates the "Structure Box" on the page.
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<StructureSection load='1eqp' size='340' side='right'caption='[[1eqp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1eqp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EQP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eqp OCA], [https://pdbe.org/1eqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eqp RCSB], [https://www.ebi.ac.uk/pdbsum/1eqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eqp ProSAT]</span></td></tr>
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{{STRUCTURE_1eqp| PDB=1eqp | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EXG1_CANAL EXG1_CANAL] Major glucan 1,3-beta-glucosidase required for cell wall integrity. Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Can also function biosynthetically as a transglycosylase. Functions to deliver glucan from the cell to the extracellular matrix. Does not appear to impact cell wall glucan content of biofilm cells, nor is it necessary for filamentation or biofilm formation. Involved in cell-substrate and cell-cell adhesion. Adhesion to host-cell surfaces is the first critical step during mucosal infection. XOG1 is target of human antimicrobial peptide LL-37 for inhibition of cell adhesion.<ref>PMID:21713010</ref> <ref>PMID:22876186</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/1eqp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eqp ConSurf].
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<div style="clear:both"></div>
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===EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS===
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==See Also==
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11112513}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11112513 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_11112513}}
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==About this Structure==
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1EQP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQP OCA].
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==Reference==
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Minor structural consequences of alternative CUG codon usage (Ser for Leu) in Candida albicans exoglucanase., Cutfield JF, Sullivan PA, Cutfield SM, Protein Eng. 2000 Oct;13(10):735-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11112513 11112513]
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[[Category: Candida albicans]]
[[Category: Candida albicans]]
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[[Category: Glucan 1,3-beta-glucosidase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Cutfield JF]]
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[[Category: Cutfield, J F.]]
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[[Category: Cutfield SM]]
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[[Category: Cutfield, S M.]]
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[[Category: Sullivan PA]]
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[[Category: Sullivan, P A.]]
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[[Category: Alternative codon usage]]
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[[Category: Candida albican]]
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[[Category: Exoglucanase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:43:40 2008''
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Current revision

EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS

PDB ID 1eqp

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