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1ezg
From Proteopedia
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| - | [[Image:1ezg.png|left|200px]] | ||
| - | + | ==CRYSTAL STRUCTURE OF ANTIFREEZE PROTEIN FROM THE BEETLE, TENEBRIO MOLITOR== | |
| - | + | <StructureSection load='1ezg' size='340' side='right'caption='[[1ezg]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ezg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tenebrio_molitor Tenebrio molitor]. The December 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Antifreeze Proteins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_12 10.2210/rcsb_pdb/mom_2009_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EZG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ezg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezg OCA], [https://pdbe.org/1ezg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ezg RCSB], [https://www.ebi.ac.uk/pdbsum/1ezg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezg ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1ezg]] is a 2 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ANPY1_TENMO ANPY1_TENMO] Contributes to protect body fluid from freezing at subzero temperatures. Lowers the freezing point of the hemolymph by about 2.5 degrees at a concentration of 1 mg/ml. Binds to nascent ice crystals and prevents further growth.<ref>PMID:10471292</ref> <ref>PMID:10833402</ref> <ref>PMID:9285581</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/1ezg_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ezg ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Antifreeze protein|Antifreeze protein]] | + | *[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Antifreeze Proteins]] | [[Category: Antifreeze Proteins]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Tenebrio molitor]] | [[Category: Tenebrio molitor]] | ||
| - | [[Category: Davies | + | [[Category: Davies PL]] |
| - | [[Category: Jia | + | [[Category: Jia Z]] |
| - | [[Category: Liou | + | [[Category: Liou Y-C]] |
| - | [[Category: Tocilj | + | [[Category: Tocilj A]] |
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Current revision
CRYSTAL STRUCTURE OF ANTIFREEZE PROTEIN FROM THE BEETLE, TENEBRIO MOLITOR
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