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1ezv

From Proteopedia

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[[Image:1ezv.png|left|200px]]
 
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{{STRUCTURE_1ezv| PDB=1ezv | SCENE= }}
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==STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT==
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<StructureSection load='1ezv' size='340' side='right'caption='[[1ezv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ezv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EZV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10873857}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SMA:STIGMATELLIN+A'>SMA</scene>, <scene name='pdbligand=UQ6:5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL'>UQ6</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ezv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezv OCA], [https://pdbe.org/1ezv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ezv RCSB], [https://www.ebi.ac.uk/pdbsum/1ezv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezv ProSAT]</span></td></tr>
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[[1ezv]] is a 11 chain structure of [[Cytochrome c]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/QCR1_YEAST QCR1_YEAST] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c. COR1 may mediate formation of the complex between cytochromes c and c1.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/1ezv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ezv ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cytochrome c|Cytochrome c]]
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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*[[Cytochrome bc1 3D structures|Cytochrome bc1 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:010873857</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Ubiquinol--cytochrome-c reductase]]
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[[Category: Hunte C]]
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[[Category: Hunte, C.]]
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[[Category: Koepke J]]
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[[Category: Koepke, J.]]
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[[Category: Lange C]]
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[[Category: Lange, C.]]
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[[Category: Michel H]]
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[[Category: Michel, H.]]
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[[Category: Rossmanith T]]
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[[Category: Rossmanith, T.]]
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[[Category: Antibody fv-fragment]]
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[[Category: Coenzyme q6]]
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[[Category: Complex iii]]
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[[Category: Cytochrome bc1 complex]]
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[[Category: Electron transfer]]
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[[Category: Matrix processing peptidase]]
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[[Category: Mitochondria]]
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[[Category: Oxidoreductase-electron transport complex]]
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[[Category: Proton transfer]]
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[[Category: Q-cycle]]
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[[Category: Qcr]]
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[[Category: Stigmatellin]]
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[[Category: Ubiquinone]]
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[[Category: Yeast]]
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Current revision

STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT

PDB ID 1ezv

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