This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1f1c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:09, 20 March 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1f1c.jpg|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF CYTOCHROME C549==
-
The line below this paragraph, containing "STRUCTURE_1f1c", creates the "Structure Box" on the page.
+
<StructureSection load='1f1c' size='340' side='right'caption='[[1f1c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1f1c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Limnospira_maxima Limnospira maxima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F1C FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
-
{{STRUCTURE_1f1c| PDB=1f1c | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f1c OCA], [https://pdbe.org/1f1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f1c RCSB], [https://www.ebi.ac.uk/pdbsum/1f1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f1c ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CY550_LIMMA CY550_LIMMA]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/1f1c_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f1c ConSurf].
 +
<div style="clear:both"></div>
-
'''CRYSTAL STRUCTURE OF CYTOCHROME C549'''
+
==See Also==
-
 
+
*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
-
 
+
__TOC__
-
==Overview==
+
</StructureSection>
-
Cytochrome c(6) and cytochrome c-549 are small (89 and 130 amino acids, respectively) monoheme cytochromes that function in photosynthesis. They appear to have descended relatively recently from the same ancestral gene but have diverged to carry out very different functional roles, underscored by the large difference between their midpoint potentials of nearly 600 mV. We have determined the X-ray crystal structures of both proteins isolated from the cyanobacterium Arthrospira maxima. The two structures are remarkably similar, superimposing on backbone atoms with an rmsd of 0.7 A. Comparison of the two structures suggests that differences in solvent exposure of the heme and the electrostatic environment of the heme propionates, as well as in heme iron ligation, are the main determinants of midpoint potential in the two proteins. In addition, the crystal packing of both A. maxima cytochrome c-549 and cytochrome c(6) suggests that the proteins oligomerize. Finally, the cytochrome c-549 dimer we observe can be readily fit into the recently described model of cyanobacterial photosystem II.
+
[[Category: Large Structures]]
-
 
+
[[Category: Limnospira maxima]]
-
==About this Structure==
+
[[Category: Kerfeld CA]]
-
1F1C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arthrospira_maxima Arthrospira maxima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1C OCA].
+
[[Category: Krogmann DW]]
-
 
+
[[Category: Sawaya MR]]
-
==Reference==
+
[[Category: Yeates TO]]
-
Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima., Sawaya MR, Krogmann DW, Serag A, Ho KK, Yeates TO, Kerfeld CA, Biochemistry. 2001 Aug 7;40(31):9215-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11478889 11478889]
+
-
[[Category: Arthrospira maxima]]
+
-
[[Category: Single protein]]
+
-
[[Category: Kerfeld, C A.]]
+
-
[[Category: Krogmann, D W.]]
+
-
[[Category: Sawaya, M R.]]
+
-
[[Category: Yeates, T O.]]
+
-
[[Category: Dimeric cytochrome]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:46:29 2008''
+

Current revision

CRYSTAL STRUCTURE OF CYTOCHROME C549

PDB ID 1f1c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1f1c"
Personal tools