1f28

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:09, 20 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1f28.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII BOUND TO DUMP AND BW1843U89==
-
The line below this paragraph, containing "STRUCTURE_1f28", creates the "Structure Box" on the page.
+
<StructureSection load='1f28' size='340' side='right'caption='[[1f28]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1f28]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F28 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F89:S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC+ACID'>F89</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
-
{{STRUCTURE_1f28| PDB=1f28 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f28 OCA], [https://pdbe.org/1f28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f28 RCSB], [https://www.ebi.ac.uk/pdbsum/1f28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f28 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_PNECA TYSY_PNECA]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/1f28_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f28 ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII BOUND TO DUMP AND BW1843U89===
+
==See Also==
-
 
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11358692}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 11358692 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_11358692}}
+
-
 
+
-
==About this Structure==
+
-
1F28 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F28 OCA].
+
-
 
+
-
==Reference==
+
-
Approaches to solving the rigid receptor problem by identifying a minimal set of flexible residues during ligand docking., Anderson AC, O'Neil RH, Surti TS, Stroud RM, Chem Biol. 2001 May;8(5):445-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11358692 11358692]
+
[[Category: Pneumocystis carinii]]
[[Category: Pneumocystis carinii]]
-
[[Category: Single protein]]
+
[[Category: Anderson AC]]
-
[[Category: Thymidylate synthase]]
+
[[Category: O'Neil RH]]
-
[[Category: Anderson, A C.]]
+
[[Category: Stroud RM]]
-
[[Category: Neil, R H.O.]]
+
[[Category: Surti TS]]
-
[[Category: Stroud, R M.]]
+
-
[[Category: Surti, T S.]]
+
-
[[Category: Beta-sheet]]
+
-
[[Category: Protein-inhibitor complex]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:21:57 2008''
+

Current revision

CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII BOUND TO DUMP AND BW1843U89

PDB ID 1f28

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1f28"
Personal tools