1f58

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{{Seed}}
 
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[[Image:1f58.png|left|200px]]
 
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==IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323==
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The line below this paragraph, containing "STRUCTURE_1f58", creates the "Structure Box" on the page.
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<StructureSection load='1f58' size='340' side='right'caption='[[1f58]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1f58]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/HIV-1_M:B_MN HIV-1 M:B_MN] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F58 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene></td></tr>
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{{STRUCTURE_1f58| PDB=1f58 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f58 OCA], [https://pdbe.org/1f58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f58 RCSB], [https://www.ebi.ac.uk/pdbsum/1f58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f58 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KV3AE_MOUSE KV3AE_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/1f58_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f58 ConSurf].
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<div style="clear:both"></div>
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===IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323===
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_10368281}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 10368281 is the PubMed ID number.
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[[Category: HIV-1 M:B_MN]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_10368281}}
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==About this Structure==
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1F58 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F58 OCA].
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==Reference==
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Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs., Stanfield R, Cabezas E, Satterthwait A, Stura E, Profy A, Wilson I, Structure. 1999 Feb 15;7(2):131-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10368281 10368281]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Cabezas E]]
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[[Category: Cabezas, E.]]
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[[Category: Profy AT]]
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[[Category: Profy, A T.]]
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[[Category: Satterthwait AC]]
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[[Category: Satterthwait, A C.]]
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[[Category: Stanfield RL]]
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[[Category: Stanfield, R L.]]
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[[Category: Stura EA]]
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[[Category: Stura, E A.]]
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[[Category: Wilson IA]]
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[[Category: Wilson, I A.]]
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[[Category: Fab]]
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[[Category: Gp120]]
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[[Category: Hiv-1]]
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[[Category: Immunoglobulin]]
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[[Category: V3]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:42:57 2008''
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Current revision

IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323

PDB ID 1f58

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