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1f9b

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[[Image:1f9b.png|left|200px]]
 
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{{STRUCTURE_1f9b| PDB=1f9b | SCENE= }}
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==MELANIN PROTEIN INTERACTION: X-RAY STRUCTURE OF THE COMPLEX OF MARE LACTOFERRIN WITH MELANIN MONOMERS==
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<StructureSection load='1f9b' size='340' side='right'caption='[[1f9b]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===MELANIN PROTEIN INTERACTION: X-RAY STRUCTURE OF THE COMPLEX OF MARE LACTOFERRIN WITH MELANIN MONOMERS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1f9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F9B FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11599026}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3ID:3H-INDOLE-5,6-DIOL'>3ID</scene>, <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f9b OCA], [https://pdbe.org/1f9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f9b RCSB], [https://www.ebi.ac.uk/pdbsum/1f9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f9b ProSAT]</span></td></tr>
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[[1f9b]] is a 1 chain structure of [[Lactoferrin]] with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9B OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRFL_HORSE TRFL_HORSE] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f9/1f9b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f9b ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Lactoferrin|Lactoferrin]]
*[[Lactoferrin|Lactoferrin]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011599026</ref><references group="xtra"/>
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[[Category: Equus caballus]]
[[Category: Equus caballus]]
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[[Category: Kumar, S.]]
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[[Category: Large Structures]]
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[[Category: Raman, G.]]
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[[Category: Kumar S]]
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[[Category: Sharma, A K.]]
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[[Category: Raman G]]
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[[Category: Singh, N.]]
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[[Category: Sharma AK]]
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[[Category: Singh, T P.]]
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[[Category: Singh N]]
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[[Category: Complex]]
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[[Category: Singh TP]]
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[[Category: Idq molecule]]
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[[Category: Iron transport]]
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[[Category: Lactoferrin]]
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[[Category: Melanin]]
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[[Category: Metal transport]]
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[[Category: Metal-binding]]
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Current revision

MELANIN PROTEIN INTERACTION: X-RAY STRUCTURE OF THE COMPLEX OF MARE LACTOFERRIN WITH MELANIN MONOMERS

PDB ID 1f9b

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