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1f9s

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{{Seed}}
 
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[[Image:1f9s.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2==
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The line below this paragraph, containing "STRUCTURE_1f9s", creates the "Structure Box" on the page.
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<StructureSection load='1f9s' size='340' side='right'caption='[[1f9s]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1f9s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F9S FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f9s OCA], [https://pdbe.org/1f9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f9s RCSB], [https://www.ebi.ac.uk/pdbsum/1f9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f9s ProSAT]</span></td></tr>
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{{STRUCTURE_1f9s| PDB=1f9s | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f9/1f9s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f9s ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2===
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==See Also==
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*[[C-X-C motif chemokine 3D structures|C-X-C motif chemokine 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1F9S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F9S OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Aster, R.]]
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[[Category: Aster R]]
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[[Category: Doyle, M.]]
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[[Category: Doyle M]]
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[[Category: Edwards, B.]]
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[[Category: Edwards B]]
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[[Category: Faulk, T.]]
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[[Category: Faulk T]]
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[[Category: Visentin, G.]]
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[[Category: Visentin G]]
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[[Category: Yang, J.]]
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[[Category: Yang J]]
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[[Category: Platelet factor 4 mutant 2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:55:45 2008''
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Current revision

CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2

PDB ID 1f9s

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