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Lactoperoxidase

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Current revision (09:39, 26 March 2024) (edit) (undo)
 
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Line 25: Line 25:
**[[7c74]] - yLPO + Cl <br />
**[[7c74]] - yLPO + Cl <br />
**[[6l32]], [[6l42]], [[7d52]], [[6l5g]], [[7c75]] - yLPO + Zn <br />
**[[6l32]], [[6l42]], [[7d52]], [[6l5g]], [[7c75]] - yLPO + Zn <br />
-
**[[6lqw]], [[6lrn]] – yPLO + H2O2<br />
+
**[[6lqw]], [[7y3u]] – yPLO + H2O2<br />
**[[7c73]] – yPLO + phosphoserine<br />
**[[7c73]] – yPLO + phosphoserine<br />
Line 60: Line 60:
**[[4ksz]] - bPLO + cystein + SCN + I<br />
**[[4ksz]] - bPLO + cystein + SCN + I<br />
**[[5wv3]] - bPLO + oxidosulfanyl-methanamine + Br + I<br />
**[[5wv3]] - bPLO + oxidosulfanyl-methanamine + Br + I<br />
-
**[[3nyh]] - bPLO + Br + Cl + SCN + I<br />
+
**[[7dlq]] - bPLO + Br + Cl + SCN + I<br />
-
**[[7vin]] - bPLO + indomethacin + SCN + I<br />
+
**[[7wyj]] - bPLO + indomethacin + SCN + I<br />
-
**[[3py4]], [[4gn6]] - bPLO + paracetamol + SCN + I<br />
+
**[[3py4]], [[6m7e]] - bPLO + paracetamol + SCN + I<br />
**[[7dn6]] - bPLO + phenyliso-SCN + SCN + I<br />
**[[7dn6]] - bPLO + phenyliso-SCN + SCN + I<br />
**[[7dn7]] - bPLO + nitro-phenoxymethanesulfonanilide+ SCN + I<br />
**[[7dn7]] - bPLO + nitro-phenoxymethanesulfonanilide+ SCN + I<br />
-
**[[3s4f]], [[4njb]], [[6lco]] - bPLO + pyridine derivative + SCN + I<br />
+
**[[8y9x]], [[4njb]], [[6lco]] - bPLO + pyridine derivative + SCN + I<br />
**[[3r4x]], [[5zgs]] - bPLO + pyrazine derivative + SCN + I<br />
**[[3r4x]], [[5zgs]] - bPLO + pyrazine derivative + SCN + I<br />
**[[3r5o]] - bPLO + methoxyphenol + SCN + I<br />
**[[3r5o]] - bPLO + methoxyphenol + SCN + I<br />
Line 80: Line 80:
**[[2efb]] – gPLO + phosphate + carbonate + SCN + CN<br />
**[[2efb]] – gPLO + phosphate + carbonate + SCN + CN<br />
**[[3qf1]] - gPLO + piperazine + SCN + I<br />
**[[3qf1]] - gPLO + piperazine + SCN + I<br />
-
**[[7wcs]] - gPLO + acrylonitrile + SCN + I<br />
+
**[[8ing]] - gPLO + acrylonitrile + SCN + I<br />
**[[4msf]], [[4oek]] - gPLO + phenol derivative+ SCN + I<br />
**[[4msf]], [[4oek]] - gPLO + phenol derivative+ SCN + I<br />
**[[2eha]] – gPLO + formate + carbonate + SCN<br />
**[[2eha]] – gPLO + formate + carbonate + SCN<br />

Current revision

Glycosylated bovine lactoferrin containing heme complex with thiocyanate, I- (purple) and Ca+2 (green) ions (PDB entry 3eri)

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3D structures of lactoperoxidase

Updated on 26-March-2024

References

  1. Gerson C, Sabater J, Scuri M, Torbati A, Coffey R, Abraham JW, Lauredo I, Forteza R, Wanner A, Salathe M, Abraham WM, Conner GE. The lactoperoxidase system functions in bacterial clearance of airways. Am J Respir Cell Mol Biol. 2000 Jun;22(6):665-71. PMID:10837362
  2. Gerson C, Sabater J, Scuri M, Torbati A, Coffey R, Abraham JW, Lauredo I, Forteza R, Wanner A, Salathe M, Abraham WM, Conner GE. The lactoperoxidase system functions in bacterial clearance of airways. Am J Respir Cell Mol Biol. 2000 Jun;22(6):665-71. PMID:10837362
  3. Sheikh IA, Singh AK, Singh N, Sinha M, Singh SB, Bhushan A, Kaur P, Srinivasan A, Sharma S, Singh TP. Structural evidence of substrate specificity in mammalian peroxidases: structure of the thiocyanate complex with lactoperoxidase and its interactions at 2.4 A resolution. J Biol Chem. 2009 May 29;284(22):14849-56. Epub 2009 Apr 1. PMID:19339248 doi:10.1074/jbc.M807644200

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Joel L. Sussman, Michal Harel, Alexander Berchansky, Jaime Prilusky

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