Cephalosporin acylase
From Proteopedia
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<StructureSection load='1jw0' size='350' side='right' caption='Cephalosporin acylase α subunit (magenta) and β subunit (green) complex with glutarate (PDB entry [[1jw0]])' scene='52/525143/Cv/1'> | <StructureSection load='1jw0' size='350' side='right' caption='Cephalosporin acylase α subunit (magenta) and β subunit (green) complex with glutarate (PDB entry [[1jw0]])' scene='52/525143/Cv/1'> | ||
- | '''Cephalosporin acylase''' (CSA) catalyzes the conversion of cephalosporin C (CPC) to 7-amino-cephalosporanic acid (7-ACA).<ref>PMID:11080627</ref> | + | '''Cephalosporin acylase''' (CSA) catalyzes the conversion of [[cephalosporin]] C (CPC) to 7-amino-cephalosporanic acid (7-ACA).<ref>PMID:11080627</ref> |
== Relevance == | == Relevance == |
Current revision
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References
- ↑ Kim Y, Yoon K, Khang Y, Turley S, Hol WG. The 2.0 A crystal structure of cephalosporin acylase. Structure. 2000 Oct 15;8(10):1059-68. PMID:11080627
- ↑ Kim Y, Hol WG. Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity. Chem Biol. 2001 Dec;8(12):1253-64. PMID:11755403