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8it4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8it4 is ON HOLD Authors: Zhou, L., Jiang, L.L. Description: Phosphoglycerate mutase 1 complexed with a covalent inhibitor [[Category: Unreleased St...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Phosphoglycerate mutase 1 complexed with a covalent inhibitor== | |
| - | + | <StructureSection load='8it4' size='340' side='right'caption='[[8it4]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8it4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IT4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SKU:3-[[5-(4-chlorophenyl)-2-methoxycarbonyl-thiophen-3-yl]sulfamoyl]benzenesulfonic+acid'>SKU</scene>, <scene name='pdbligand=TYB:TYROSINAL'>TYB</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8it4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8it4 OCA], [https://pdbe.org/8it4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8it4 RCSB], [https://www.ebi.ac.uk/pdbsum/8it4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8it4 ProSAT]</span></td></tr> |
| - | [[Category: Jiang | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Jiang LL]] | ||
| + | [[Category: Zhou L]] | ||
Current revision
Phosphoglycerate mutase 1 complexed with a covalent inhibitor
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