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8too
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12== | |
| - | + | <StructureSection load='8too' size='340' side='right'caption='[[8too]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8too]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_4 Human gammaherpesvirus 4] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TOO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8too FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8too OCA], [https://pdbe.org/8too PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8too RCSB], [https://www.ebi.ac.uk/pdbsum/8too PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8too ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GP42_EBVB9 GP42_EBVB9] Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells.<ref>PMID:12042810</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human gammaherpesvirus 4]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Board N]] | ||
| + | [[Category: Bu W]] | ||
| + | [[Category: Cohen JI]] | ||
| + | [[Category: Dowdell K]] | ||
| + | [[Category: Hostal A]] | ||
| + | [[Category: Kim J]] | ||
| + | [[Category: Krogmann T]] | ||
| + | [[Category: Kumar A]] | ||
| + | [[Category: Lei Y]] | ||
| + | [[Category: Marcotrigiano J]] | ||
| + | [[Category: Pittaluga S]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Zhang S]] | ||
Current revision
Crystal structure of Epstein-Barr virus gp42 in complex with antibody 4C12
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Categories: Human gammaherpesvirus 4 | Large Structures | Mus musculus | Board N | Bu W | Cohen JI | Dowdell K | Hostal A | Kim J | Krogmann T | Kumar A | Lei Y | Marcotrigiano J | Pittaluga S | Wang Y | Zhang S
