2hg5
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2hg5.png|left|200px]] | ||
| - | + | ==Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter== | |
| - | + | <StructureSection load='2hg5' size='340' side='right'caption='[[2hg5]], [[Resolution|resolution]] 2.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2hg5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HG5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HG5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3H:(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL+NONANOATE'>B3H</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GOA:GLYCOLIC+ACID'>GOA</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hg5 OCA], [https://pdbe.org/2hg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hg5 RCSB], [https://www.ebi.ac.uk/pdbsum/2hg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hg5 ProSAT]</span></td></tr> |
| - | [[2hg5]] | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q569B4_RAT Q569B4_RAT] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hg/2hg5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hg5 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Monoclonal | + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] |
| - | *[[Potassium | + | *[[Potassium channel 3D structures|Potassium channel 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: | + | [[Category: Streptomyces lividans]] |
| - | [[Category: | + | [[Category: MacKinnon R]] |
| - | [[Category: | + | [[Category: Muir TW]] |
| - | [[Category: | + | [[Category: Valiyaveetil FI]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter
| |||||||||||
