2hg5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:15, 27 March 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2hg5.png|left|200px]]
 
-
<!--
+
==Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter==
-
The line below this paragraph, containing "STRUCTURE_2hg5", creates the "Structure Box" on the page.
+
<StructureSection load='2hg5' size='340' side='right'caption='[[2hg5]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2hg5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HG5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HG5 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3H:(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL+NONANOATE'>B3H</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GOA:GLYCOLIC+ACID'>GOA</scene></td></tr>
-
{{STRUCTURE_2hg5| PDB=2hg5 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hg5 OCA], [https://pdbe.org/2hg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hg5 RCSB], [https://www.ebi.ac.uk/pdbsum/2hg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hg5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q569B4_RAT Q569B4_RAT]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hg/2hg5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hg5 ConSurf].
 +
<div style="clear:both"></div>
-
===Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter===
+
==See Also==
-
 
+
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
-
 
+
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_16939283}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 16939283 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
-
{{ABSTRACT_PUBMED_16939283}}
+
-
 
+
-
==About this Structure==
+
-
2HG5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HG5 OCA].
+
-
 
+
-
==Reference==
+
-
Structural and functional consequences of an amide-to-ester substitution in the selectivity filter of a potassium channel., Valiyaveetil FI, Sekedat M, MacKinnon R, Muir TW, J Am Chem Soc. 2006 Sep 6;128(35):11591-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16939283 16939283]
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Single protein]]
+
[[Category: Streptomyces lividans]]
-
[[Category: MacKinnon, R.]]
+
[[Category: MacKinnon R]]
-
[[Category: Muir, T W.]]
+
[[Category: Muir TW]]
-
[[Category: Valiyaveetil, F I.]]
+
[[Category: Valiyaveetil FI]]
-
[[Category: Channel]]
+
-
[[Category: Ester]]
+
-
[[Category: Semi-synthetic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:56:46 2008''
+

Current revision

Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter

PDB ID 2hg5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2hg5"
Personal tools