5xi5

<StructureSection load='5xi5' size='340' side='right' caption='[[5xi5]], [[Resolution|resolution]] 2.81&Aring;' scene=''>

<table><tr><td colspan='2'>[[5xi5]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Sus_barbatus Sus barbatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XI5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XI5 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PN6:(3Z,6Z)-3-BENZYLIDENE-6-[(5-TERT-BUTYL-1H-IMIDAZOL-4-YL)METHYLIDENE]PIPERAZINE-2,5-DIONE'>PN6</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xi5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xi5 OCA], [http://pdbe.org/5xi5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xi5 RCSB], [http://www.ebi.ac.uk/pdbsum/5xi5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xi5 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/A0A0R4I993_SUSBA A0A0R4I993_SUSBA]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00824325] [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/A0A0R4I995_SUSBA A0A0R4I995_SUSBA]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00103861]

[[Category: Chu, Y]]

[[Category: Li, W]]

[[Category: Wang, Y]]

[[Category: Yang, J]]

[[Category: Tubulin]]