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5yo2

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==The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with Acetyl CoA and L-Arginine==
==The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with Acetyl CoA and L-Arginine==
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<StructureSection load='5yo2' size='340' side='right' caption='[[5yo2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='5yo2' size='340' side='right'caption='[[5yo2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yo2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YO2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YO2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.997&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2747 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amino-acid_N-acetyltransferase Amino-acid N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.1 2.3.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yo2 OCA], [https://pdbe.org/5yo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yo2 RCSB], [https://www.ebi.ac.uk/pdbsum/5yo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yo2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yo2 OCA], [http://pdbe.org/5yo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5yo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yo2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARGA_MYCTU ARGA_MYCTU]] Catalyzes the conversion of L-glutamate to alpha-N-acetyl-L-glutamate. L-glutamine is a significantly better substrate compared to L-glutamate.<ref>PMID:15838030</ref>
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[https://www.uniprot.org/uniprot/ARGA_MYCTU ARGA_MYCTU] Catalyzes the conversion of L-glutamate to alpha-N-acetyl-L-glutamate. L-glutamine is a significantly better substrate compared to L-glutamate.<ref>PMID:15838030</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Amino-acid N-acetyltransferase]]
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[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Das, U]]
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[[Category: Das U]]
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[[Category: Gourinath, S]]
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[[Category: Gourinath S]]
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[[Category: Pal, R K]]
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[[Category: Pal RK]]
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[[Category: Singh, E]]
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[[Category: Singh E]]
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[[Category: Srinivasan, A]]
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[[Category: Srinivasan A]]
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[[Category: Subhramanyam, U K.Tiruttani]]
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[[Category: Tiruttani Subhramanyam UK]]
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[[Category: Acetyltransferase]]
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[[Category: Transferase]]
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Current revision

The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with Acetyl CoA and L-Arginine

PDB ID 5yo2

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