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5zym
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5zym is ON HOLD Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K. D...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of CERT START domain in complex with compound E25B== | |
| - | + | <StructureSection load='5zym' size='340' side='right'caption='[[5zym]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5zym]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZYM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9M6:2-[4-[4-cyclopentyl-3-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9M6</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zym OCA], [https://pdbe.org/5zym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zym RCSB], [https://www.ebi.ac.uk/pdbsum/5zym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zym ProSAT]</span></td></tr> |
| - | [[Category: Hanada | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry. |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Ueno | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Egawa D]] | ||
| + | [[Category: Hanada K]] | ||
| + | [[Category: Hanzawa H]] | ||
| + | [[Category: Kawasaki S]] | ||
| + | [[Category: Kobayashi S]] | ||
| + | [[Category: Kumagai K]] | ||
| + | [[Category: Nakao N]] | ||
| + | [[Category: Sakai S]] | ||
| + | [[Category: Suzuki M]] | ||
| + | [[Category: Ueno M]] | ||
Current revision
Crystal structure of CERT START domain in complex with compound E25B
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Categories: Homo sapiens | Large Structures | Egawa D | Hanada K | Hanzawa H | Kawasaki S | Kobayashi S | Kumagai K | Nakao N | Sakai S | Suzuki M | Ueno M
