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6ahc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of aldehyde-alcohol dehydrogenase reveals a high-order helical architecture critical for its activity== | |
| + | <SX load='6ahc' size='340' side='right' viewer='molstar' caption='[[6ahc]], [[Resolution|resolution]] 3.45Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ahc]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AHC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.45Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ahc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ahc OCA], [https://pdbe.org/6ahc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ahc RCSB], [https://www.ebi.ac.uk/pdbsum/6ahc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ahc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADHE_ECOLI ADHE_ECOLI] This enzyme has three activities: ADH, ACDH, and PFL-deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction. | ||
| - | + | ==See Also== | |
| - | + | *[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| - | [[Category: Kim | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: Song | + | [[Category: Large Structures]] |
| + | [[Category: Kim G]] | ||
| + | [[Category: Song JJ]] | ||
Current revision
Cryo-EM structure of aldehyde-alcohol dehydrogenase reveals a high-order helical architecture critical for its activity
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