6jql

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m (Protected "6jql" [edit=sysop:move=sysop])
Current revision (10:39, 27 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6jql is ON HOLD
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==Structure of PaaZ, a bifunctional enzyme==
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<SX load='6jql' size='340' side='right' viewer='molstar' caption='[[6jql]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Sathyanarayanan, N., Cannone, G., Gakher, L., Katagihallimath, N., Sowdhamini, R., Ramaswamy, S., Vinothkumar, K.R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6jql]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JQL FirstGlance]. <br>
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Description: Structure of PaaZ, a bifunctional enzyme
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jql OCA], [https://pdbe.org/6jql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jql RCSB], [https://www.ebi.ac.uk/pdbsum/6jql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jql ProSAT]</span></td></tr>
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[[Category: Ramaswamy, S]]
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</table>
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[[Category: Cannone, G]]
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== Function ==
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[[Category: Katagihallimath, N]]
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[https://www.uniprot.org/uniprot/PAAZ_ECOLI PAAZ_ECOLI] Catalyzes the hydrolytic ring cleavage of 2-oxepin-2(3H)-ylideneacetyl-CoA (oxepin-CoA) via the open-chain aldehyde intermediate to yield 3-oxo-5,6-dehydrosuberyl-CoA. The enzyme consists of a C-terminal (R)-specific enoyl-CoA hydratase domain (formerly MaoC) that cleaves the ring and produces the highly reactive 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde and an N-terminal NADP-dependent aldehyde dehydrogenase domain that oxidizes the aldehyde to 3-oxo-5,6-dehydrosuberyl-CoA. Can also use crotonyl-CoA as substrate.<ref>PMID:20660314</ref> <ref>PMID:21296885</ref> <ref>PMID:9748275</ref>
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[[Category: Vinothkumar, K.R]]
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== References ==
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[[Category: Sathyanarayanan, N]]
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<references/>
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[[Category: Sowdhamini, R]]
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__TOC__
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[[Category: Gakher, L]]
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</SX>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Cannone G]]
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[[Category: Gakher L]]
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[[Category: Katagihallimath N]]
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[[Category: Sathyanarayanan N]]
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[[Category: Sowdhamini R]]
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[[Category: Vinothkumar KR]]

Current revision

Structure of PaaZ, a bifunctional enzyme

6jql, resolution 2.90Å

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