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6jyl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry 6jyl is | + | ==The crosslinked complex of ISWI-nucleosome in the ADP.BeF-bound state== |
| + | <SX load='6jyl' size='340' side='right' viewer='molstar' caption='[[6jyl]], [[Resolution|resolution]] 3.37Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6jyl]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6irm 6irm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JYL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.37Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jyl OCA], [https://pdbe.org/6jyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jyl RCSB], [https://www.ebi.ac.uk/pdbsum/6jyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jyl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| - | + | ==See Also== | |
| - | + | *[[Histone 3D structures|Histone 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: Gao | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: | + | [[Category: Xenopus laevis]] |
| - | [[Category: Wu | + | [[Category: Chen ZC]] |
| + | [[Category: Gao N]] | ||
| + | [[Category: Li XM]] | ||
| + | [[Category: Wu H]] | ||
| + | [[Category: Yan LJ]] | ||
Current revision
The crosslinked complex of ISWI-nucleosome in the ADP.BeF-bound state
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