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6l8o
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==Crystal structure of the K. lactis Rad5 (Hg-derivative)== | ==Crystal structure of the K. lactis Rad5 (Hg-derivative)== | ||
| - | <StructureSection load='6l8o' size='340' side='right'caption='[[6l8o]]' scene=''> | + | <StructureSection load='6l8o' size='340' side='right'caption='[[6l8o]], [[Resolution|resolution]] 3.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8O OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6l8o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis_NRRL_Y-1140 Kluyveromyces lactis NRRL Y-1140]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L8O FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8o OCA], [https://pdbe.org/6l8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l8o RCSB], [https://www.ebi.ac.uk/pdbsum/6l8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RAD5_KLULA RAD5_KLULA] Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Kluyveromyces lactis NRRL Y-1140]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Shen M]] | [[Category: Shen M]] | ||
[[Category: Xiang S]] | [[Category: Xiang S]] | ||
Current revision
Crystal structure of the K. lactis Rad5 (Hg-derivative)
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