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1akg

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{{Seed}}
 
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[[Image:1akg.png|left|200px]]
 
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==ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS==
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The line below this paragraph, containing "STRUCTURE_1akg", creates the "Structure Box" on the page.
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<StructureSection load='1akg' size='340' side='right'caption='[[1akg]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1akg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_pennaceus Conus pennaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AKG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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{{STRUCTURE_1akg| PDB=1akg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1akg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1akg OCA], [https://pdbe.org/1akg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1akg RCSB], [https://www.ebi.ac.uk/pdbsum/1akg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1akg ProSAT]</span></td></tr>
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</table>
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===ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS===
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== Function ==
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[https://www.uniprot.org/uniprot/CA1B_CONPE CA1B_CONPE] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian nAChRs (alpha-7 > alpha-3/beta-2).<ref>PMID:10545176</ref>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_8068627}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 8068627 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_8068627}}
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==About this Structure==
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1AKG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Conus_pennaceus Conus pennaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AKG OCA].
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==Reference==
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New mollusc-specific alpha-conotoxins block Aplysia neuronal acetylcholine receptors., Fainzilber M, Hasson A, Oren R, Burlingame AL, Gordon D, Spira ME, Zlotkin E, Biochemistry. 1994 Aug 16;33(32):9523-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8068627 8068627]
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[[Category: Conus pennaceus]]
[[Category: Conus pennaceus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Hu, S H.]]
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[[Category: Hu S-H]]
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[[Category: Martin, J L.]]
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[[Category: Martin JL]]
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[[Category: Acetylcholine receptor antagonist]]
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[[Category: Alpha-conotoxin]]
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[[Category: Crystal structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:02:14 2008''
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Current revision

ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS

PDB ID 1akg

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