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1flj

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[[Image:1flj.png|left|200px]]
 
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{{STRUCTURE_1flj| PDB=1flj | SCENE= }}
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==CRYSTAL STRUCTURE OF S-GLUTATHIOLATED CARBONIC ANHYDRASE III==
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<StructureSection load='1flj' size='340' side='right'caption='[[1flj]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF S-GLUTATHIOLATED CARBONIC ANHYDRASE III===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1flj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLJ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11024467}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flj OCA], [https://pdbe.org/1flj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flj RCSB], [https://www.ebi.ac.uk/pdbsum/1flj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flj ProSAT]</span></td></tr>
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[[1flj]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLJ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAH3_RAT CAH3_RAT] Reversible hydration of carbon dioxide. A major participant in the liver response to oxidative stress.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1flj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1flj ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Carbonic anhydrase|Carbonic anhydrase]]
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011024467</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Carbonate dehydratase]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Chatterjee, T K.]]
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[[Category: Chatterjee TK]]
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[[Category: Darmawan, S.]]
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[[Category: Darmawan S]]
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[[Category: Fisher, R A.]]
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[[Category: Fisher RA]]
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[[Category: Honzatko, R B.]]
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[[Category: Honzatko RB]]
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[[Category: Mallis, R J.]]
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[[Category: Mallis RJ]]
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[[Category: Poland, B W.]]
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[[Category: Poland BW]]
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[[Category: Thomas, J A.]]
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[[Category: Thomas JA]]
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[[Category: Carbonic anhydrase iii]]
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[[Category: Glutathione]]
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[[Category: Lyase]]
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[[Category: S-glutathiolated]]
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[[Category: S-glutathionylated]]
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Current revision

CRYSTAL STRUCTURE OF S-GLUTATHIOLATED CARBONIC ANHYDRASE III

PDB ID 1flj

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