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1flw

From Proteopedia

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{{Seed}}
 
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[[Image:1flw.png|left|200px]]
 
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<!--
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==HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE==
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The line below this paragraph, containing "STRUCTURE_1flw", creates the "Structure Box" on the page.
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<StructureSection load='1flw' size='340' side='right'caption='[[1flw]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1flw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.812&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flw OCA], [https://pdbe.org/1flw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flw RCSB], [https://www.ebi.ac.uk/pdbsum/1flw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flw ProSAT]</span></td></tr>
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{{STRUCTURE_1flw| PDB=1flw | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1flw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1flw ConSurf].
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<div style="clear:both"></div>
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===HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE===
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==See Also==
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11112507}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11112507 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_11112507}}
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==About this Structure==
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1FLW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLW OCA].
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==Reference==
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Relationship between local structure and stability in hen egg white lysozyme mutant with alanine substituted for glycine., Masumoto K, Ueda T, Motoshima H, Imoto T, Protein Eng. 2000 Oct;13(10):691-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11112507 11112507]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Imoto T]]
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[[Category: Imoto, T.]]
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[[Category: Masumoto K]]
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[[Category: Masumoto, K.]]
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[[Category: Motoshima H]]
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[[Category: Motoshima, H.]]
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[[Category: Ueda T]]
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[[Category: Ueda, T.]]
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[[Category: Alanine scanning]]
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[[Category: Hen lysozyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:27:42 2008''
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Current revision

HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE

PDB ID 1flw

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