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1fm5

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{{Seed}}
 
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[[Image:1fm5.png|left|200px]]
 
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<!--
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==CRYSTAL STRUCTURE OF HUMAN CD69==
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The line below this paragraph, containing "STRUCTURE_1fm5", creates the "Structure Box" on the page.
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<StructureSection load='1fm5' size='340' side='right'caption='[[1fm5]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fm5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FM5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fm5 OCA], [https://pdbe.org/1fm5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fm5 RCSB], [https://www.ebi.ac.uk/pdbsum/1fm5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fm5 ProSAT]</span></td></tr>
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{{STRUCTURE_1fm5| PDB=1fm5 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CD69_HUMAN CD69_HUMAN] Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/1fm5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fm5 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF HUMAN CD69===
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==See Also==
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*[[CD69|CD69]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11101293}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11101293 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_11101293}}
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==About this Structure==
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1FM5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FM5 OCA].
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==Reference==
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Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells., Natarajan K, Sawicki MW, Margulies DH, Mariuzza RA, Biochemistry. 2000 Dec 5;39(48):14779-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11101293 11101293]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Margulies, D H.]]
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[[Category: Margulies DH]]
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[[Category: Mariuzza, R A.]]
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[[Category: Mariuzza RA]]
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[[Category: Natarajan, K.]]
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[[Category: Natarajan K]]
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[[Category: Sawicki, M W.]]
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[[Category: Sawicki MW]]
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[[Category: C-type lectin]]
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[[Category: C-type lectin-like domain]]
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[[Category: Lectin]]
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[[Category: Natural killer cell receptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:28:21 2008''
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Current revision

CRYSTAL STRUCTURE OF HUMAN CD69

PDB ID 1fm5

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