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1fmx

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{{Seed}}
 
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[[Image:1fmx.png|left|200px]]
 
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==STRUCTURE OF NATIVE PROTEINASE A IN THE SPACE GROUP P21==
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The line below this paragraph, containing "STRUCTURE_1fmx", creates the "Structure Box" on the page.
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<StructureSection load='1fmx' size='340' side='right'caption='[[1fmx]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fmx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FMX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1fmx| PDB=1fmx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fmx OCA], [https://pdbe.org/1fmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fmx RCSB], [https://www.ebi.ac.uk/pdbsum/1fmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fmx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_YEAST CARP_YEAST] Aspartyl protease implicated in the post-translational regulation of S.cerevisiae vacuolar proteinases. Acts on YSCB, on YSCY and on itself.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/1fmx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fmx ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF NATIVE PROTEINASE A IN THE SPACE GROUP P21===
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==See Also==
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*[[Pepsin|Pepsin]]
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*[[Proteinase 3D structures|Proteinase 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_12127998}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 12127998 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_12127998}}
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==About this Structure==
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1FMX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FMX OCA].
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==Reference==
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An unusual orientation for Tyr75 in the active site of the aspartic proteinase from Saccharomyces cerevisiae., Gustchina A, Li M, Phylip LH, Lees WE, Kay J, Wlodawer A, Biochem Biophys Res Commun. 2002 Jul 26;295(4):1020-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12127998 12127998]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Saccharopepsin]]
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[[Category: Gustchina A]]
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[[Category: Single protein]]
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[[Category: Kay J]]
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[[Category: Gustchina, A.]]
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[[Category: Lees WE]]
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[[Category: Kay, J.]]
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[[Category: Li M]]
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[[Category: Lees, W E.]]
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[[Category: Phylip LH]]
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[[Category: Li, M.]]
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[[Category: Wlodawer A]]
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[[Category: Phylip, L H.]]
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[[Category: Wlodawer, A.]]
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[[Category: Proteinase some]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:33:01 2008''
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Current revision

STRUCTURE OF NATIVE PROTEINASE A IN THE SPACE GROUP P21

PDB ID 1fmx

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