1fnx

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{{Seed}}
 
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[[Image:1fnx.png|left|200px]]
 
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==SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT==
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The line below this paragraph, containing "STRUCTURE_1fnx", creates the "Structure Box" on the page.
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<StructureSection load='1fnx' size='340' side='right'caption='[[1fnx]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fnx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FNX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fnx OCA], [https://pdbe.org/1fnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fnx RCSB], [https://www.ebi.ac.uk/pdbsum/1fnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fnx ProSAT]</span></td></tr>
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{{STRUCTURE_1fnx| PDB=1fnx | SCENE= }}
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</table>
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== Function ==
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===SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT===
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[https://www.uniprot.org/uniprot/ELAV3_MOUSE ELAV3_MOUSE] Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance.<ref>PMID:9016658</ref> <ref>PMID:10734193</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1FNX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNX OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/1fnx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fnx ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Hirao, M.]]
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[[Category: Hirao M]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kasashima, K.]]
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[[Category: Kasashima K]]
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[[Category: Kawai, G.]]
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[[Category: Kawai G]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Kim, I S.]]
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[[Category: Kim I-S]]
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[[Category: Muto, Y.]]
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[[Category: Muto Y]]
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[[Category: Sakamoto, H.]]
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[[Category: Sakamoto H]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: Protein-rna complex]]
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[[Category: Rna-binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:09:24 2009''
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Current revision

SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT

PDB ID 1fnx

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OCA

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