This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1fq4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:15, 27 March 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1fq4.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A==
-
The line below this paragraph, containing "STRUCTURE_1fq4", creates the "Structure Box" on the page.
+
<StructureSection load='1fq4' size='340' side='right'caption='[[1fq4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1fq4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FQ4 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2Y2:N-[(2R)-1-{[(2S,3R,5R)-1-CYCLOHEXYL-3-HYDROXY-5-{[2-(MORPHOLIN-4-YL)ETHYL]CARBAMOYL}OCT-7-YN-2-YL]AMINO}-3-(METHYLSULFANYL)-1-OXOPROPAN-2-YL]-1H-BENZIMIDAZOLE-2-CARBOXAMIDE'>2Y2</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
{{STRUCTURE_1fq4| PDB=1fq4 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fq4 OCA], [https://pdbe.org/1fq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fq4 RCSB], [https://www.ebi.ac.uk/pdbsum/1fq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fq4 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CARP_YEAST CARP_YEAST] Aspartyl protease implicated in the post-translational regulation of S.cerevisiae vacuolar proteinases. Acts on YSCB, on YSCY and on itself.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fq/1fq4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fq4 ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A===
+
==See Also==
-
 
+
*[[Pepsin|Pepsin]]
-
 
+
*[[Proteinase 3D structures|Proteinase 3D structures]]
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_11061973}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 11061973 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
-
{{ABSTRACT_PUBMED_11061973}}
+
-
 
+
-
==About this Structure==
+
-
1FQ4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQ4 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:11061973</ref><references group="xtra"/>
+
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Saccharopepsin]]
+
[[Category: Badasso MO]]
-
[[Category: Badasso, M O.]]
+
[[Category: Cooper JB]]
-
[[Category: Cooper, J B.]]
+
[[Category: Cronin NB]]
-
[[Category: Cronin, N B.]]
+
[[Category: Dreyer T]]
-
[[Category: Dreyer, T.]]
+
[[Category: Hoover DJ]]
-
[[Category: Hoover, D J.]]
+
[[Category: Humblet CC]]
-
[[Category: Humblet, C C.]]
+
[[Category: Lunney EA]]
-
[[Category: Lunney, E A.]]
+
[[Category: Rosati RL]]
-
[[Category: Rosati, R L.]]
+
[[Category: Tickle IJ]]
-
[[Category: Tickle, I J.]]
+
-
[[Category: Aspartic proteinase/inhibitor complex]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:21:49 2009''
+

Current revision

CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A

PDB ID 1fq4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fq4"
Personal tools