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1fuj

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{{Seed}}
 
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[[Image:1fuj.png|left|200px]]
 
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<!--
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==PR3 (MYELOBLASTIN)==
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The line below this paragraph, containing "STRUCTURE_1fuj", creates the "Structure Box" on the page.
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<StructureSection load='1fuj' size='340' side='right'caption='[[1fuj]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fuj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FUJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1fuj| PDB=1fuj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fuj OCA], [https://pdbe.org/1fuj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fuj RCSB], [https://www.ebi.ac.uk/pdbsum/1fuj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fuj ProSAT]</span></td></tr>
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</table>
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===PR3 (MYELOBLASTIN)===
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== Function ==
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[https://www.uniprot.org/uniprot/PRTN3_HUMAN PRTN3_HUMAN] Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_8757293}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 8757293 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/1fuj_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_8757293}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1FUJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FUJ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fuj ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies., Fujinaga M, Chernaia MM, Halenbeck R, Koths K, James MN, J Mol Biol. 1996 Aug 16;261(2):267-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8757293 8757293]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Chernaia, M M.]]
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[[Category: Chernaia MM]]
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[[Category: Fujinaga, M.]]
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[[Category: Fujinaga M]]
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[[Category: Halenbeck, R.]]
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[[Category: Halenbeck R]]
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[[Category: James, M N.G.]]
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[[Category: James MNG]]
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[[Category: Koths, K.]]
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[[Category: Koths K]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Serine protease]]
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[[Category: Signal]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:58:04 2008''
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Current revision

PR3 (MYELOBLASTIN)

PDB ID 1fuj

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