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1fyl

From Proteopedia

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{{Seed}}
 
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[[Image:1fyl.png|left|200px]]
 
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==SERENDIPITOUS CRYSTAL STRUCTURE CONTAINING THE HEAT SHOCK TRANSCRIPTION FACTOR'S DNA BINDING DOMAIN AND COGNATE DNA IN A HEAD-TO-HEAD ORIENTATION==
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The line below this paragraph, containing "STRUCTURE_1fyl", creates the "Structure Box" on the page.
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<StructureSection load='1fyl' size='340' side='right'caption='[[1fyl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1fyl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FYL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1fyl| PDB=1fyl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fyl OCA], [https://pdbe.org/1fyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fyl RCSB], [https://www.ebi.ac.uk/pdbsum/1fyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fyl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HSF_KLULA HSF_KLULA] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. Also required for growth at normal temperatures.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/1fyl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fyl ConSurf].
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<div style="clear:both"></div>
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===SERENDIPITOUS CRYSTAL STRUCTURE CONTAINING THE HEAT SHOCK TRANSCRIPTION FACTOR'S DNA BINDING DOMAIN AND COGNATE DNA IN A HEAD-TO-HEAD ORIENTATION===
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==See Also==
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*[[Heat shock factor|Heat shock factor]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11599025}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 11599025 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11599025}}
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==About this Structure==
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1FYL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FYL OCA].
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==Reference==
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Crystal packing interaction that blocks crystallization of a site-specific DNA binding protein-DNA complex., Littlefield O, Nelson HC, Proteins. 2001 Nov 15;45(3):219-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11599025 11599025]
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[[Category: Kluyveromyces lactis]]
[[Category: Kluyveromyces lactis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Littlefield, O.]]
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[[Category: Littlefield O]]
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[[Category: Nelson, H C.M.]]
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[[Category: Nelson HCM]]
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[[Category: Crystal-packing interface]]
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[[Category: Crystallization]]
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[[Category: Protein-dna interface]]
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[[Category: Protein-protein interface]]
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[[Category: Static disorder]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:08:08 2008''
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Current revision

SERENDIPITOUS CRYSTAL STRUCTURE CONTAINING THE HEAT SHOCK TRANSCRIPTION FACTOR'S DNA BINDING DOMAIN AND COGNATE DNA IN A HEAD-TO-HEAD ORIENTATION

PDB ID 1fyl

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