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1g68

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{{Seed}}
 
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[[Image:1g68.png|left|200px]]
 
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==PSE-4 CARBENICILLINASE, WILD TYPE==
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The line below this paragraph, containing "STRUCTURE_1g68", creates the "Structure Box" on the page.
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<StructureSection load='1g68' size='340' side='right'caption='[[1g68]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1g68]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G68 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1g68| PDB=1g68 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g68 OCA], [https://pdbe.org/1g68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g68 RCSB], [https://www.ebi.ac.uk/pdbsum/1g68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g68 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLP4_PSEAI BLP4_PSEAI] Hydrolyzes both carbenicillin and oxacillin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/1g68_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g68 ConSurf].
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<div style="clear:both"></div>
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===PSE-4 CARBENICILLINASE, WILD TYPE===
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11148033}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11148033 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_11148033}}
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==About this Structure==
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1G68 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G68 OCA].
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==Reference==
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Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies., Lim D, Sanschagrin F, Passmore L, De Castro L, Levesque RC, Strynadka NC, Biochemistry. 2001 Jan 16;40(2):395-402. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11148033 11148033]
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[[Category: Beta-lactamase]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Single protein]]
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[[Category: De Castro L]]
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[[Category: Castro, L De.]]
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[[Category: Levesque RC]]
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[[Category: Levesque, R C.]]
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[[Category: Lim D]]
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[[Category: Lim, D.]]
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[[Category: Passmore L]]
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[[Category: Passmore, L.]]
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[[Category: Sanschagrin F]]
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[[Category: Sanschagrin, F.]]
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[[Category: Strynadka NCJ]]
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[[Category: Strynadka, N C.J.]]
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[[Category: Carbenicillinase]]
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[[Category: Class a beta-lactamase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 04:37:11 2008''
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Current revision

PSE-4 CARBENICILLINASE, WILD TYPE

PDB ID 1g68

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