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1gec

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{{Seed}}
 
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[[Image:1gec.png|left|200px]]
 
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<!--
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==GLYCYL ENDOPEPTIDASE-COMPLEX WITH BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE COVALENTLY BOUND TO CYSTEINE 25==
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The line below this paragraph, containing "STRUCTURE_1gec", creates the "Structure Box" on the page.
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<StructureSection load='1gec' size='340' side='right'caption='[[1gec]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1gec]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GEC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0HQ:DIAZOMETHANE'>0HQ</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>
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{{STRUCTURE_1gec| PDB=1gec | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gec OCA], [https://pdbe.org/1gec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gec RCSB], [https://www.ebi.ac.uk/pdbsum/1gec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gec ProSAT]</span></td></tr>
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</table>
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===GLYCYL ENDOPEPTIDASE-COMPLEX WITH BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE COVALENTLY BOUND TO CYSTEINE 25===
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== Function ==
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[https://www.uniprot.org/uniprot/PAPA4_CARPA PAPA4_CARPA] Thiol protease with a substrate specificity very different from the other thiol proteases.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_7548082}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 7548082 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/1gec_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_7548082}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1GEC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GEC OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gec ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of glycyl endopeptidase from Carica papaya: a cysteine endopeptidase of unusual substrate specificity., O'Hara BP, Hemmings AM, Buttle DJ, Pearl LH, Biochemistry. 1995 Oct 10;34(40):13190-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7548082 7548082]
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</StructureSection>
[[Category: Carica papaya]]
[[Category: Carica papaya]]
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[[Category: Glycyl endopeptidase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Buttle DJ]]
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[[Category: Buttle, D J.]]
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[[Category: Hemmings AM]]
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[[Category: Hemmings, A M.]]
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[[Category: Ohara BP]]
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[[Category: Ohara, B P.]]
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[[Category: Pearl LH]]
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[[Category: Pearl, L H.]]
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[[Category: Hydrolysis]]
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[[Category: Inhibitor complex]]
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[[Category: Proteinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 05:09:51 2008''
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Current revision

GLYCYL ENDOPEPTIDASE-COMPLEX WITH BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE COVALENTLY BOUND TO CYSTEINE 25

PDB ID 1gec

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