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1gmx
From Proteopedia
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| - | [[Image:1gmx.png|left|200px]] | ||
| - | + | ==Escherichia coli GlpE sulfurtransferase== | |
| - | + | <StructureSection load='1gmx' size='340' side='right'caption='[[1gmx]], [[Resolution|resolution]] 1.10Å' scene=''> | |
| - | === | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1gmx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GMX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gmx OCA], [https://pdbe.org/1gmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gmx RCSB], [https://www.ebi.ac.uk/pdbsum/1gmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gmx ProSAT]</span></td></tr> |
| - | [[1gmx]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLPE_ECOLI GLPE_ECOLI] Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. The relatively low affinity of GlpE for both thiosulfate and cyanide suggests that these compounds are not the physiological substrates. Thioredoxin 1 or related dithiol proteins could instead be the physiological sulfur-acceptor substrate. Possible association with the metabolism of glycerol-phosphate remains to be elucidated.[HAMAP-Rule:MF_01009] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gmx_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gmx ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Sulfurtransferase|Sulfurtransferase]] | *[[Sulfurtransferase|Sulfurtransferase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | [[Category: Bolognesi M]] |
| - | [[Category: Bolognesi | + | [[Category: Bordo D]] |
| - | [[Category: Bordo | + | [[Category: Donahue JT]] |
| - | [[Category: Donahue | + | [[Category: Larson TJ]] |
| - | [[Category: Larson | + | [[Category: Spallarossa A]] |
| - | [[Category: Spallarossa | + | |
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Current revision
Escherichia coli GlpE sulfurtransferase
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