This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1h03

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:26, 27 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1h03.png|left|200px]]
 
-
<!--
+
==Human CD55 domains 3 & 4==
-
The line below this paragraph, containing "STRUCTURE_1h03", creates the "Structure Box" on the page.
+
<StructureSection load='1h03' size='340' side='right'caption='[[1h03]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1h03]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H03 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H03 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h03 OCA], [https://pdbe.org/1h03 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h03 RCSB], [https://www.ebi.ac.uk/pdbsum/1h03 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h03 ProSAT]</span></td></tr>
-
{{STRUCTURE_1h03| PDB=1h03 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/1h03_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h03 ConSurf].
 +
<div style="clear:both"></div>
-
===HUMAN CD55 DOMAINS 3 & 4===
+
==See Also==
-
 
+
*[[CD55|CD55]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_12499389}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 12499389 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_12499389}}
+
-
 
+
-
==About this Structure==
+
-
[[1h03]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H03 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:12499389</ref><ref group="xtra">PMID:10329784</ref><ref group="xtra">PMID:9804811</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Billington, J.]]
+
[[Category: Large Structures]]
-
[[Category: Chaudhry, Y.]]
+
[[Category: Billington J]]
-
[[Category: Evans, D J.]]
+
[[Category: Chaudhry Y]]
-
[[Category: Goodfellow, I.]]
+
[[Category: Evans DJ]]
-
[[Category: Lea, S M.]]
+
[[Category: Goodfellow I]]
-
[[Category: Spiller, B.]]
+
[[Category: Lea SM]]
-
[[Category: Williams, P.]]
+
[[Category: Spiller B]]
-
[[Category: Alternative splicing]]
+
[[Category: Williams P]]
-
[[Category: Bacterial receptor]]
+
-
[[Category: Complement decay accelerating factor]]
+
-
[[Category: Complement pathway]]
+
-
[[Category: Enteroviral receptor]]
+
-
[[Category: Gpi-anchor]]
+
-
[[Category: Immune system protein]]
+
-
[[Category: Ligand for cd97]]
+

Current revision

Human CD55 domains 3 & 4

PDB ID 1h03

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h03"
Personal tools