1h0m

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{{Seed}}
 
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[[Image:1h0m.png|left|200px]]
 
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==Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA==
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The line below this paragraph, containing "STRUCTURE_1h0m", creates the "Structure Box" on the page.
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<StructureSection load='1h0m' size='340' side='right'caption='[[1h0m]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1h0m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0M FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LAE:3-OXO-OCTANOIC+ACID+(2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE'>LAE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1h0m| PDB=1h0m | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0m OCA], [https://pdbe.org/1h0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0m RCSB], [https://www.ebi.ac.uk/pdbsum/1h0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0m ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRAR_RHIRD TRAR_RHIRD] Positive regulation of conjugal transfer of Ti plasmids. TraR activates target genes in the presence of AAI and also activates traR and traI themselves.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/1h0m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h0m ConSurf].
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<div style="clear:both"></div>
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===THREE-DIMENSIONAL STRUCTURE OF THE QUORUM SENSING PROTEIN TRAR BOUND TO ITS AUTOINDUCER AND TO ITS TARGET DNA===
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12198141}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12198141 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12198141}}
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==About this Structure==
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1H0M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0M OCA].
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==Reference==
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The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA., Vannini A, Volpari C, Gargioli C, Muraglia E, Cortese R, De Francesco R, Neddermann P, Marco SD, EMBO J. 2002 Sep 2;21(17):4393-401. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12198141 12198141]
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[[Category: Agrobacterium tumefaciens]]
[[Category: Agrobacterium tumefaciens]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Cortese, R.]]
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[[Category: Synthetic construct]]
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[[Category: Francesco, R De.]]
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[[Category: Cortese R]]
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[[Category: Gargioli, C.]]
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[[Category: De Francesco R]]
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[[Category: Marco, S Di.]]
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[[Category: Di Marco S]]
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[[Category: Muraglia, E.]]
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[[Category: Gargioli C]]
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[[Category: Neddermann, P.]]
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[[Category: Muraglia E]]
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[[Category: Vannini, A.]]
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[[Category: Neddermann P]]
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[[Category: Volpari, C.]]
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[[Category: Vannini A]]
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[[Category: Dna-binding protein]]
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[[Category: Volpari C]]
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[[Category: Homoserine lactone]]
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[[Category: Luxr-type protein]]
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[[Category: Quorum sensing]]
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[[Category: Transcriptional regulator]]
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[[Category: Trar]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:25:21 2008''
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Current revision

Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA

PDB ID 1h0m

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