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1h8s

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{{Seed}}
 
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[[Image:1h8s.png|left|200px]]
 
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==Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with the hapten.==
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The line below this paragraph, containing "STRUCTURE_1h8s", creates the "Structure Box" on the page.
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<StructureSection load='1h8s' size='340' side='right'caption='[[1h8s]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1h8s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H8S FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIC:(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>AIC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1h8s| PDB=1h8s | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h8s OCA], [https://pdbe.org/1h8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h8s RCSB], [https://www.ebi.ac.uk/pdbsum/1h8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h8s ProSAT]</span></td></tr>
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</table>
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===THREE-DIMENSIONAL STRUCTURE OF ANTI-AMPICILLIN SINGLE CHAIN FV FRAGMENT COMPLEXED WITH THE HAPTEN.===
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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The line below this paragraph, {{ABSTRACT_PUBMED_11397088}}, adds the Publication Abstract to the page
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/1h8s_consurf.spt"</scriptWhenChecked>
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(as it appears on PubMed at http://www.pubmed.gov), where 11397088 is the PubMed ID number.
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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{{ABSTRACT_PUBMED_11397088}}
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h8s ConSurf].
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==About this Structure==
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<div style="clear:both"></div>
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1H8S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mouse_e_010090 Mouse e 010090]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8S OCA].
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__TOC__
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</StructureSection>
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==Reference==
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[[Category: Large Structures]]
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Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries., Burmester J, Spinelli S, Pugliese L, Krebber A, Honegger A, Jung S, Schimmele B, Cambillau C, Pluckthun A, J Mol Biol. 2001 Jun 8;309(3):671-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11397088 11397088]
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[[Category: Mus musculus]]
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[[Category: Mouse e 010090]]
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[[Category: Burmester J]]
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[[Category: Single protein]]
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[[Category: Cambillau C]]
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[[Category: Burmester, J.]]
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[[Category: Honegger A]]
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[[Category: Cambillau, C.]]
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[[Category: Jung S]]
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[[Category: Honegger, A.]]
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[[Category: Krebber A]]
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[[Category: Jung, S.]]
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[[Category: Pluckthun A]]
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[[Category: Krebber, A.]]
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[[Category: Pugliese L]]
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[[Category: Pluckthun, A.]]
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[[Category: Schimmele B]]
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[[Category: Pugliese, L.]]
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[[Category: Spinelli S]]
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[[Category: Schimmele, B.]]
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[[Category: Spinelli, S.]]
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[[Category: Anti-ampicillin antibody]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:49:03 2008''
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Current revision

Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with the hapten.

PDB ID 1h8s

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