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1hfg

From Proteopedia

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{{Seed}}
 
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[[Image:1hfg.png|left|200px]]
 
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<!--
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==NMR solution structure of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus (minimized average structure).==
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The line below this paragraph, containing "STRUCTURE_1hfg", creates the "Structure Box" on the page.
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<StructureSection load='1hfg' size='340' side='right'caption='[[1hfg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hfg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HFG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HFG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hfg OCA], [https://pdbe.org/1hfg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hfg RCSB], [https://www.ebi.ac.uk/pdbsum/1hfg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hfg ProSAT]</span></td></tr>
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{{STRUCTURE_1hfg| PDB=1hfg | SCENE= }}
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</table>
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== Function ==
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===NMR SOLUTION STRUCTURE OF VMIP-II 1-71 FROM KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS (MINIMIZED AVERAGE STRUCTURE).===
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[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11165244}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11165244 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/1hfg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11165244}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hfg ConSurf].
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1HFG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HFG OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structure/function of human herpesvirus-8 MIP-II (1-71) and the antagonist N-terminal segment (1-10)., Crump MP, Elisseeva E, Gong J, Clark-Lewis I, Sykes BD, FEBS Lett. 2001 Feb 2;489(2-3):171-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11165244 11165244]
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[[Category: Human gammaherpesvirus 8]]
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[[Category: Human herpesvirus 8]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Clark-Lewis I]]
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[[Category: Clark-Lewis, I.]]
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[[Category: Crump MP]]
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[[Category: Crump, M P.]]
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[[Category: Elisseeva E]]
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[[Category: Elisseeva, E.]]
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[[Category: Gong J-H]]
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[[Category: Gong, J H.]]
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[[Category: Sykes BD]]
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[[Category: Sykes, B D.]]
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[[Category: Anatagonist]]
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[[Category: Chemokine]]
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[[Category: Cxcr4]]
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[[Category: Vmip-ii]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:06:52 2008''
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Current revision

NMR solution structure of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus (minimized average structure).

PDB ID 1hfg

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