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1hfn
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1hfn.png|left|200px]] | ||
| - | + | ==NMR solution structures of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus.== | |
| - | + | <StructureSection load='1hfn' size='340' side='right'caption='[[1hfn]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1hfn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HFN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hfn OCA], [https://pdbe.org/1hfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hfn RCSB], [https://www.ebi.ac.uk/pdbsum/1hfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hfn ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | < | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/1hfn_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hfn ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | < | + | [[Category: Human gammaherpesvirus 8]] |
| - | [[ | + | [[Category: Large Structures]] |
| - | [ | + | [[Category: Clark-Lewis I]] |
| - | [[ | + | [[Category: Crump MP]] |
| - | [[Category: | + | [[Category: Elisseeva E]] |
| - | [[Category: | + | [[Category: Gong J-H]] |
| - | [[Category: | + | [[Category: Sykes BD]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
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Current revision
NMR solution structures of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus.
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