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1hi7

From Proteopedia

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{{Seed}}
 
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[[Image:1hi7.png|left|200px]]
 
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==NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1hi7", creates the "Structure Box" on the page.
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<StructureSection load='1hi7' size='340' side='right'caption='[[1hi7]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hi7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HI7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi7 OCA], [https://pdbe.org/1hi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hi7 RCSB], [https://www.ebi.ac.uk/pdbsum/1hi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi7 ProSAT]</span></td></tr>
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{{STRUCTURE_1hi7| PDB=1hi7 | SCENE= }}
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</table>
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== Function ==
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===NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES===
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[https://www.uniprot.org/uniprot/TFF1_HUMAN TFF1_HUMAN] Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.<ref>PMID:16308573</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11286998}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11286998 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/1hi7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11286998}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hi7 ConSurf].
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1HI7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI7 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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The solution structure of the disulphide-linked homodimer of the human trefoil protein TFF1., Williams MA, Westley BR, May FE, Feeney J, FEBS Lett. 2001 Mar 30;493(2-3):70-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11286998 11286998]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Feeney, J.]]
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[[Category: Feeney J]]
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[[Category: Williams, M A.]]
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[[Category: Williams MA]]
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[[Category: Cell motility]]
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[[Category: Growth factor]]
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[[Category: Signal]]
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[[Category: Trefoil domain]]
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[[Category: Tumor suppressor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:13:11 2008''
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Current revision

NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES

PDB ID 1hi7

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