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1hul

From Proteopedia

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{{Seed}}
 
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[[Image:1hul.png|left|200px]]
 
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==A NOVEL DIMER CONFIGURATION REVEALED BY THE CRYSTAL STRUCTURE AT 2.4 ANGSTROMS RESOLUTION OF HUMAN INTERLEUKIN-5==
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The line below this paragraph, containing "STRUCTURE_1hul", creates the "Structure Box" on the page.
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<StructureSection load='1hul' size='340' side='right'caption='[[1hul]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hul]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HUL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hul OCA], [https://pdbe.org/1hul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hul RCSB], [https://www.ebi.ac.uk/pdbsum/1hul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hul ProSAT]</span></td></tr>
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{{STRUCTURE_1hul| PDB=1hul | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IL5_HUMAN IL5_HUMAN] Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/1hul_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hul ConSurf].
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<div style="clear:both"></div>
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===A NOVEL DIMER CONFIGURATION REVEALED BY THE CRYSTAL STRUCTURE AT 2.4 ANGSTROMS RESOLUTION OF HUMAN INTERLEUKIN-5===
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==See Also==
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*[[Interleukin 3D structures|Interleukin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8483502}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8483502 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8483502}}
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==About this Structure==
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1HUL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HUL OCA].
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==Reference==
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A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5., Milburn MV, Hassell AM, Lambert MH, Jordan SR, Proudfoot AE, Graber P, Wells TN, Nature. 1993 May 13;363(6425):172-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8483502 8483502]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Milburn, M V.]]
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[[Category: Milburn MV]]
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[[Category: Cytokine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 08:42:59 2008''
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Current revision

A NOVEL DIMER CONFIGURATION REVEALED BY THE CRYSTAL STRUCTURE AT 2.4 ANGSTROMS RESOLUTION OF HUMAN INTERLEUKIN-5

PDB ID 1hul

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