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='''Glucagon-Like Peptide 1 Receptor (GLP1-R)'''= | ='''Glucagon-Like Peptide 1 Receptor (GLP1-R)'''= | ||
== Introduction == | == Introduction == | ||
| - | <StructureSection load='Receptor/1' size='340' side='right' caption='Caption for this structure' scene=''> | + | <StructureSection load='Receptor/1' size='340' side='right' caption='Caption for this structure' scene='10/1038821/Receptor/1'> |
Glucagon-Like Peptide 1 Receptor or GLP1-R uses the glucagon-like peptide to signal the body to secrete insulin and inhibit glucagon secretion. When glucose levels in the blood rise (usually after consuming food), GLP-1R activates, creating a signaling cascade to signal cAMP. After the signaling cascade, the final result is the secretion of insulin to the rest of the body. | Glucagon-Like Peptide 1 Receptor or GLP1-R uses the glucagon-like peptide to signal the body to secrete insulin and inhibit glucagon secretion. When glucose levels in the blood rise (usually after consuming food), GLP-1R activates, creating a signaling cascade to signal cAMP. After the signaling cascade, the final result is the secretion of insulin to the rest of the body. | ||
Revision as of 14:13, 28 March 2024
Glucagon-Like Peptide 1 Receptor (GLP1-R)
Introduction
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References
- ↑ Zhang LQ, Zhang W, Li T, Yang T, Yuan X, Zhou Y, Zou Q, Yang H, Gao F, Tian Y, Mei W, Tian XB. GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice. Neurobiol Learn Mem. 2021 Jul;182:107463. PMID:34015440 doi:10.1016/j.nlm.2021.107463
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

