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8wfl
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8wfl is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==human glycine transporter 1 in complex with PF-03463275 in outward facing conformation== | |
| - | + | <StructureSection load='8wfl' size='340' side='right'caption='[[8wfl]], [[Resolution|resolution]] 3.03Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8wfl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WFL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.03Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=W5X:PF-3463275'>W5X</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wfl OCA], [https://pdbe.org/8wfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wfl RCSB], [https://www.ebi.ac.uk/pdbsum/8wfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wfl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SC6A9_HUMAN SC6A9_HUMAN] Atypical glycine encephalopathy;Infantile glycine encephalopathy. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SC6A9_HUMAN SC6A9_HUMAN] Sodium- and chloride-dependent glycine transporter (PubMed:8183239). Essential for regulating glycine concentrations at inhibitory glycinergic synapses.[UniProtKB:P28571]<ref>PMID:8183239</ref> Sodium- and chloride-dependent glycine transporter.<ref>PMID:8183239</ref> Sodium- and chloride-dependent glycine transporter.<ref>PMID:8183239</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wei Y]] | ||
| + | [[Category: Zhao Y]] | ||
Current revision
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
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