This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8wqi
From Proteopedia
(Difference between revisions)
m (Protected "8wqi" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Local refinement of FEM1B bound with the C-degron of CUX1== | |
| - | + | <StructureSection load='8wqi' size='340' side='right'caption='[[8wqi]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8wqi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WQI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WQI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wqi OCA], [https://pdbe.org/8wqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wqi RCSB], [https://www.ebi.ac.uk/pdbsum/8wqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wqi ProSAT]</span></td></tr> |
| - | [[Category: Chen | + | </table> |
| - | [[Category: Xu | + | == Function == |
| - | [[Category: Zhang | + | [https://www.uniprot.org/uniprot/FEM1B_HUMAN FEM1B_HUMAN] Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.<ref>PMID:10542291</ref> <ref>PMID:19330022</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen X]] | ||
| + | [[Category: Xu C]] | ||
| + | [[Category: Zhang K]] | ||
Current revision
Local refinement of FEM1B bound with the C-degron of CUX1
| |||||||||||
Categories: Homo sapiens | Large Structures | Chen X | Xu C | Zhang K
