1ci7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:57, 3 April 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ci7.png|left|200px]]
 
-
{{STRUCTURE_1ci7| PDB=1ci7 | SCENE= }}
+
==TERNARY COMPLEX OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII==
-
 
+
<StructureSection load='1ci7' size='340' side='right'caption='[[1ci7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-
===TERNARY COMPLEX OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1ci7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CI7 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_10529228}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CB3:10-PROPARGYL-5,8-DIDEAZAFOLIC+ACID'>CB3</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ci7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ci7 OCA], [https://pdbe.org/1ci7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ci7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ci7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ci7 ProSAT]</span></td></tr>
-
[[1ci7]] is a 2 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CI7 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_PNECA TYSY_PNECA]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/1ci7_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ci7 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Thymidylate synthase|Thymidylate synthase]]
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:010529228</ref><references group="xtra"/>
+
[[Category: Large Structures]]
[[Category: Pneumocystis carinii]]
[[Category: Pneumocystis carinii]]
-
[[Category: Thymidylate synthase]]
+
[[Category: Anderson AC]]
-
[[Category: Anderson, A C.]]
+
[[Category: Delano WL]]
-
[[Category: Delano, W L.]]
+
[[Category: O'Neil RH]]
-
[[Category: Neil, R H.O.]]
+
[[Category: Stroud RM]]
-
[[Category: Stroud, R M.]]
+
-
[[Category: Half-sites reactivity]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: Nucleotide biosynthesis]]
+
-
[[Category: Transferase]]
+

Current revision

TERNARY COMPLEX OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII

PDB ID 1ci7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools